Introduction

This project aims to create a robust network of African scientists – within and outside Africa– in collaboration with leading researchers around the world, who use the latest genetics and genomics science to contribute towards malaria elimination efforts in Africa. By combining data from across the continent and from across human, parasite, and vector samples, PAMGEN will better understand the deadly evolutionary arms race of malaria.

Objectives & Coordination

The three goals of PAMGEN are to:

1. Create sustainable, innovative strategies and methods to collect, manage, share and analyse standardised data on human and parasite genetic variation, gene-disease associtions, and gene-environment interactions
2. Nurture African leadership by identifying and training the next generation of African researchers through advanced degree programmes in genetics and genomics; large-scal datga analysis; and bioethics.
3. Use human, parasite, and vector population and functional genomics research to drive the development of new tools to support malaria elimination programmes across Africa.

Sampling locations

Cameroon, Ethiopia, The Gambia, Ghana, Madagascar, Mali, Tanzania.

PAMGEN sites

Partner studies

The project is divided into four separate studies, according to P. falciparum parasite data, P. vivax parasite data, vector data and human data.