Partner study description

In collaboration with colleagues at the MRC Unit The Gambia, Alfred Amambua Ngwa is investigating the population structure and signatures of selection from immunity and drugs in isolated and cross-border Plasmodium falciparum populations. He uses whole genome sequencing and targeted genotyping to analyse such populations across geopolitical borders and islands in West Africa. This study is contributing to the Plasmodium Diversity Network Africa (PDNA), an African-led network investigating the genetic diversity and drug resistance of Plasmodium parasites across Africa.