Partner study description

Abdoulaye Djimdé at the Malaria Research and Training Centre at the University of Bamako and Oumou Maïga-Ascofaré are investigating the genetic signature of drug pressure on Plasmodium falciparum parasites collected in a seasonal transmission areas in Southern Mali. Samples collected before and after the introduction of artemisinin-based combination therapy (ACT) are compared for signatures of a recent positive selection. This study is contributing to the Plasmodium Diversity Network Africa (PDNA), an African-led network investigating the genetic diversity and drug resistance of Plasmodium parasites across Africa.